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2013 ; 3
(2
): 242-271
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Nanostructured Biomaterials and Their Applications
#MMPMID28348334
Parratt K
; Yao N
Nanomaterials (Basel)
2013[May]; 3
(2
): 242-271
PMID28348334
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Some of the most important advances in the life sciences have come from
transitioning to thinking of materials and their properties on the nanoscale
rather than the macro or even microscale. Improvements in imaging technology have
allowed us to see nanofeatures that directly impact chemical and mechanical
properties of natural and man-made materials. Now that these can be imaged and
quantified, substantial advances have been made in the fields of biomimetics,
tissue engineering, and drug delivery. For the first time, scientists can
determine the importance of nanograins and nanoasperities in nacre, direct the
nucleation of apatite and the growth of cells on nanostructured scaffolds, and
pass drugs tethered to nanoparticles through the blood-brain barrier. This review
examines some of the most interesting materials whose nanostructure and
hierarchical organization have been shown to correlate directly with favorable
properties and their resulting applications.
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