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2014 ; 9
(5
): 560-573
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Nano-imaging enabled via self-assembly
#MMPMID25506387
McLeod E
; Ozcan A
Nano Today
2014[Oct]; 9
(5
): 560-573
PMID25506387
show ga
Imaging object details with length scales below approximately 200 nm has been
historically difficult for conventional microscope objective lenses because of
their inability to resolve features smaller than one-half the optical wavelength.
Here we review some of the recent approaches to surpass this limit by harnessing
self-assembly as a fabrication mechanism. Self-assembly can be used to form
individual nano- and micro-lenses, as well as to form extended arrays of such
lenses. These lenses have been shown to enable imaging with resolutions as small
as 50 nm half-pitch using visible light, which is well below the Abbe diffraction
limit. Furthermore, self-assembled nano-lenses can be used to boost contrast and
signal levels from small nano-particles, enabling them to be detected relative to
background noise. Finally, alternative nano-imaging applications of self-assembly
are discussed, including three-dimensional imaging, enhanced coupling from
light-emitting diodes, and the fabrication of contrast agents such as quantum
dots and nanoparticles.
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