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10.1155/2017/4817275

http://scihub22266oqcxt.onion/10.1155/2017/4817275
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suck abstract from ncbi


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pmid28695037
      Case+Rep+Rheumatol 2017 ; 2017 (ä): 4817275
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  • NXP-2 Positive Dermatomyositis: A Unique Clinical Presentation #MMPMID28695037
  • Butt Z ; Patel L ; Das MK ; Mecoli CA ; Ramji A
  • Case Rep Rheumatol 2017[]; 2017 (ä): 4817275 PMID28695037 show ga
  • Dermatomyositis (DM), a myopathy associated with inflammation and muscle weakness, has historically been difficult to diagnose. Recently, nuclear matrix protein (NXP-2) antibodies have been described as a myositis-specific antibody that may aid in the diagnostic evaluation. We present the case of a 21-year-old, previously healthy, African American male with DM. He presented to our outpatient clinic with periorbital swelling and a rash, for which he was started on prednisone by an ophthalmologist. Towards the end of the prednisone taper, he began to experience muscle weakness, a worsening rash, and dysphagia to solids with a resultant loss of 60 pounds within a month. He was transferred to a tertiary care hospital where he was further evaluated and ultimately diagnosed with dermatomyositis, supported by skin and muscle biopsies, and was found to be positive for NXP-2. He was given intravenous immunoglobulin (IVIG) and high-dose steroids with improvement.
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