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2017 ; 130
(8
): 958-959
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NR4A proteins and neutrophil lifespan
#MMPMID28838938
Allen LH
Blood
2017[Aug]; 130
(8
): 958-959
PMID28838938
show ga
In this issue of Blood, Prince et al provide fundamental insight into the
function of proteins in the NR4A orphan nuclear receptor protein family,
identifying NR4A2 and NR4A3 as critical regulators of neutrophil lifespan and
homeostasis, and demonstrating that they act via a cyclic adenosine monophosphate
(cAMP) and protein kinase A (PKA)?dependent mechanism.
|*Neutrophils
[MESH]
|*Nuclear Receptor Subfamily 4, Group A, Member 2
[MESH]