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Myricetin: A Dietary Molecule with Diverse Biological Activities
#MMPMID26891321
Semwal DK
; Semwal RB
; Combrinck S
; Viljoen A
Nutrients
2016[Feb]; 8
(2
): 90
PMID26891321
show ga
Myricetin is a common plant-derived flavonoid and is well recognised for its
nutraceuticals value. It is one of the key ingredients of various foods and
beverages. The compound exhibits a wide range of activities that include strong
anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities. It
displays several activities that are related to the central nervous system and
numerous studies have suggested that the compound may be beneficial to protect
against diseases such as Parkinson's and Alzheimer's. The use of myricetin as a
preserving agent to extend the shelf life of foods containing oils and fats is
attributed to the compound's ability to protect lipids against oxidation. A
detailed search of existing literature revealed that there is currently no
comprehensive review available on this important molecule. Hence, the present
work includes the history, synthesis, pharmaceutical applications and toxicity
studies of myricetin. This report also highlights structure-activity
relationships and mechanisms of action for various biological activities.
|*Diet
[MESH]
|*Phytotherapy
[MESH]
|Animals
[MESH]
|Anti-Infective Agents/*pharmacology/therapeutic use
[MESH]
|Antineoplastic Agents, Phytogenic/*pharmacology/therapeutic use
[MESH]
|Antioxidants/*pharmacology/therapeutic use
[MESH]
|Flavonoids/*pharmacology/therapeutic use
[MESH]
|Humans
[MESH]
|Nervous System Diseases/prevention & control
[MESH]
|Neuroprotective Agents/*pharmacology/therapeutic use
[MESH]
|Plant Extracts/pharmacology/therapeutic use
[MESH]
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