Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25313349
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Curr+Opin+Chem+Eng
2014 ; 6
(ä): 18-24
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Multiscale Models of Antibiotic Probiotics
#MMPMID25313349
Kaznessis YN
Curr Opin Chem Eng
2014[Nov]; 6
(ä): 18-24
PMID25313349
show ga
The discovery of antibiotics is one of the most important advances in the history
of humankind. For eighty years human life expectancy and standards of living
improved greatly thanks to antibiotics. But bacteria have been fighting back,
developing resistance to our most potent molecules. New, alternative strategies
must be explored as antibiotic therapies become obsolete because of bacterial
resistance. Mathematical models and simulations guide the development of complex
technologies, such as aircrafts, bridges, communication systems and
transportation systems. Herein, models are discussed that guide the development
of new antibiotic technologies. These models span multiple molecular and cellular
scales, and facilitate the development of a technology that addresses a
significant societal challenge. We argue that simulations can be a creative
source of knowledge.