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2015 ; 56
(6
): e96-9
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Multimodality imaging of splenic sclerosing angiomatoid nodular transformation
#MMPMID26106250
Lim HT
; Tan CH
; Teo LT
; Ho CS
Singapore Med J
2015[Jun]; 56
(6
): e96-9
PMID26106250
show ga
Sclerosing angiomatoid nodular transformation (SANT) is an exceedingly rare,
benign and proliferative vascular lesion that arises from the splenic red pulp.
It is often an incidental finding on imaging. The diagnosis of SANT is confirmed
via histopathological examination of the resected spleen. Herein, we present a
case of SANT and describe its typical imaging characteristics. An asymptomatic
39-year-old man was found to have a 3.1 cm × 2.7 cm × 2.3 cm hypoechoic splenic
lesion during abdominal ultrasonography, which was performed to investigate his
elevated gamma-glutamyl transpeptidase and alanine transaminase levels.
Contrast-enhanced computed tomography suggested a vascular splenic lesion, while
magnetic resonance imaging demonstrated features consistent with SANT. In view of
the increasing size of the lesion on follow-up imaging, the patient elected for
splenectomy. Histopathological examination confirmed SANT, and the lesion was
completely resected by laparoscopic splenectomy.