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10.1038/srep27142 http://scihub22266oqcxt.onion/10.1038/srep27142 C4901393!4901393 !27283889     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27283889 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Rep 2016 ; 6 (ä): 27142 Nephropedia Template TP {{tp|p=27283889 |t=2016. Moxifloxacin: Clinically compatible contrast agent for multiphoton imaging |pdf=|usr=}}{{27283889 }} gab.com Text Moxifloxacin: Clinically compatible contrast agent for multiphoton imaging JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27283889 #FOAvip Multiphoton microscopy (MPM) is a nonlinear fluorescence microscopic technique widely used for cellular imaging of thick tissues and live animals in biological studies. However, MPM application to human tissues is limited by weak endogenous fluorescence in tissue and cytotoxicity of exogenous probes. Herein, we describe the applications of moxifloxacin, an FDA-approved antibiotic, as a cell-labeling agent for MPM. Moxifloxacin has bright intrinsic multiphoton fluorescence, good tissue penetration and high intracellular concentration. MPM with moxifloxacin was demonstrated in various cell lines, and animal tissues of cornea, skin, small intestine and bladder. Clinical application is promising since imaging based on moxifloxacin labeling could be 10 times faster than imaging based on endogenous fluorescence. Twit Text FOAVip Moxifloxacin: Clinically compatible contrast agent for multiphoton imaging ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27283889 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27283889 #FOAvip English Wikipedia <ref>{{Cite pmid|27283889 }}</ref> Moxifloxacin: Clinically compatible contrast agent for multiphoton imaging #MMPMID27283889 Wang T ; Jang WH ; Lee S ; Yoon CJ ; Lee JH ; Kim B ; Hwang S ; Hong CP ; Yoon Y ; Lee G ; Le VH ; Bok S ; Ahn GO ; Lee J ; Gho YS ; Chung E ; Kim S ; Jang MH ; Myung SJ ; Kim MJ ; So PT ; Kim KH Sci Rep 2016[Jun]; 6 (ä): 27142 PMID27283889 show ga Multiphoton microscopy (MPM) is a nonlinear fluorescence microscopic technique widely used for cellular imaging of thick tissues and live animals in biological studies. However, MPM application to human tissues is limited by weak endogenous fluorescence in tissue and cytotoxicity of exogenous probes. Herein, we describe the applications of moxifloxacin, an FDA-approved antibiotic, as a cell-labeling agent for MPM. Moxifloxacin has bright intrinsic multiphoton fluorescence, good tissue penetration and high intracellular concentration. MPM with moxifloxacin was demonstrated in various cell lines, and animal tissues of cornea, skin, small intestine and bladder. Clinical application is promising since imaging based on moxifloxacin labeling could be 10 times faster than imaging based on endogenous fluorescence. |Animals [MESH] |Contrast Media/*metabolism [MESH] |Cornea/metabolism [MESH] |Fluoroquinolones/*metabolism [MESH] |HT29 Cells [MESH] |Humans [MESH] |Intestine, Small/metabolism [MESH] |Mice [MESH] |Microscopy, Fluorescence, Multiphoton/*methods [MESH] |Moxifloxacin [MESH] |NIH 3T3 Cells [MESH] |Skin/metabolism [MESH] |Tissue Distribution [MESH]Moxifloxacin: Clinically compatible contrast agent for multiphoton ima(epmc).pdf DeepDyve Pubget Overpricing