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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Pediatric+Infect+Dis+Soc
2014 ; 3 Suppl 1
(Suppl 1
): S36-40
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Mother-to-Child Transmission of Trypanosoma cruzi
#MMPMID25232476
Gebrekristos HT
; Buekens P
J Pediatric Infect Dis Soc
2014[Sep]; 3 Suppl 1
(Suppl 1
): S36-40
PMID25232476
show ga
Among the world's most neglected tropical diseases, Chagas disease is
vector-borne and caused by Trypanosoma cruzi. T cruzi infection is endemic to
South and Central America as well as Mexico. Due to population migration, T cruzi
is increasingly becoming a public health problem in nonendemic settings. Success
with vector control strategies has led to a relative increase in the burden
attributable to congenital transmission of T cruzi. In endemic settings,
approximately 5% of infected pregnant women transmit to their offspring.
Congenital T cruzi infection is generally asymptomatic and parasitological and
serological testing is required for diagnosis. This review highlights research
gaps with a focus on (1) improving screening, diagnostic, and treatment options
and (2) designing epidemiologic studies to understand risk factors for congenital
T cruzi.