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2015 ; 3
(6
): 821-826
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Molecular characterization of human Torque Teno virus
#MMPMID26623023
Wei Y
; Chen M
; Yang X
; Zhang L
; Rao L
; Yuan F
; Wang Y
; Gong J
; Li L
Biomed Rep
2015[Nov]; 3
(6
): 821-826
PMID26623023
show ga
The present study analyzed the presence of human Torque Teno virus (TTV) in
hospitalized patients from different departments. In total, 378 serum specimens
were collected from the patients (171 with cardiovascular disease, 192 with tumor
and 15 with gastroenteritis) and analyzed by ELISA and nest-polymerase chain
reaction (PCR) to detect the presence of TTV. The results showed that 64
specimens (17%) were TTV positive from detection with the human ELISA kit, and
the patients aged <30 years have a higher prevalence. TTV in males was more
common than in female patients. In addition, nest-PCR was used to detect TTV
within different phylogenetic groups among the 64 specimens, and the results
showed that groups 1 (TA278 strain), 4 (KC009) and 5 (CT39) were much more
prevalent than groups 2 (PMV isolate) and 3 (11 genotypes) in the different
departmental patients.