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10.1002/9781118755815.ch01

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C4318123!4318123 !25663722
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suck abstract from ncbi

pmid25663722
      Adv+Chem+Phys 2014 ; 155 (?): 1-68
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  • Modeling Viral Capsid Assembly #MMPMID25663722
  • Hagan MF
  • Adv Chem Phys 2014[]; 155 (?): 1-68 PMID25663722 show ga
  • I present a review of the theoretical and computational methodologies that have been used to model the assembly of viral capsids. I discuss the capabilities and limitations of approaches ranging from equilibrium continuum theories to molecular dynamics simulations, and I give an overview of some of the important conclusions about virus assembly that have resulted from these modeling efforts. Topics include the assembly of empty viral shells, assembly around single-stranded nucleic acids to form viral particles, and assembly around synthetic polymers or charged nanoparticles for nanotechnology or biomedical applications. I present some examples in which modeling efforts have promoted experimental breakthroughs, as well as directions in which the connection between modeling and experiment can be strengthened.
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