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10.2147/EB.S16192 http://scihub22266oqcxt.onion/10.2147/EB.S16192 C5436186!5436186 !28539774     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28539774 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Eye+Brain 2011 ; 3 (ä): 29-47 Nephropedia Template TP {{tp|p=28539774 |t=2011. Mitochondrial disorders and the eye |pdf=|usr=}}{{28539774 }} gab.com Text Mitochondrial disorders and the eye JO: Eye Brain http://www.kidney.de/pget.php?&tw=1&pmid=28539774 #FOAvip The clinical significance of disturbed mitochondrial function in the eye has emerged since mitochondrial DNA (mtDNA) mutation was described in Leber's hereditary optic neuropathy. The spectrum of mitochondrial dysfunction has become apparent through increased understanding of the contribution of nuclear and somatic mtDNA mutations to mitochondrial dynamics and function. Common ophthalmic manifestations of mitochondrial dysfunction include optic atrophy, pigmentary retinopathy, and ophthalmoplegia. The majority of patients with ocular manifestations of mitochondrial disease also have variable central and peripheral nervous system involvement. Mitochondrial dysfunction has recently been associated with age-related retinal disease including macular degeneration and glaucoma. Therefore, therapeutic targets directed at promoting mitochondrial biogenesis and function offer a potential to both preserve retinal function and attenuate neurodegenerative processes. Twit Text FOAVip Mitochondrial disorders and the eye ????Eye Brain http://www.kidney.de/pget.php?&tw=1&pmid=28539774 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28539774 #FOAvip English Wikipedia <ref>{{Cite pmid|28539774 }}</ref> Mitochondrial disorders and the eye #MMPMID28539774 Van Bergen NJ ; Chakrabarti R ; O'Neill EC ; Crowston JG ; Trounce IA Eye Brain 2011[]; 3 (ä): 29-47 PMID28539774 show ga The clinical significance of disturbed mitochondrial function in the eye has emerged since mitochondrial DNA (mtDNA) mutation was described in Leber's hereditary optic neuropathy. The spectrum of mitochondrial dysfunction has become apparent through increased understanding of the contribution of nuclear and somatic mtDNA mutations to mitochondrial dynamics and function. Common ophthalmic manifestations of mitochondrial dysfunction include optic atrophy, pigmentary retinopathy, and ophthalmoplegia. The majority of patients with ocular manifestations of mitochondrial disease also have variable central and peripheral nervous system involvement. Mitochondrial dysfunction has recently been associated with age-related retinal disease including macular degeneration and glaucoma. Therefore, therapeutic targets directed at promoting mitochondrial biogenesis and function offer a potential to both preserve retinal function and attenuate neurodegenerative processes. äMitochondrial disorders and the eye (epmc).pdf DeepDyve Pubget Overpricing