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2013 ; 13
(3
): 342-9
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Mimics of pancreatic ductal adenocarcinoma
#MMPMID24060833
Al-Hawary MM
; Kaza RK
; Azar SF
; Ruma JA
; Francis IR
Cancer Imaging
2013[Sep]; 13
(3
): 342-9
PMID24060833
show ga
Several uncommon primary pancreatic tumors, inflammatory conditions, metastasis
to the pancreas and peripancreatic masses can mimic the appearance of pancreatic
ductal adenocarcinoma (PDA). Differentiation between these lesions and PDA can be
challenging, due to the overlap in imaging features; however, familiarity with
their typical imaging features and clinical presentation may be helpful in their
differentiation, as in some cases, invasive diagnostic tests or unnecessary
surgery can be avoided. The different pathologies that can mimic PDA include
inflammatory conditions such as the various forms of pancreatitis (chronic-focal
mass-forming, autoimmune and groove pancreatitis), pancreatic neuroendocrine
tumors, solid pseudopapillary tumors, metastasis (solid non-lymphomatous and
hematologic), congenital variants (annular pancreas), as well as peripancreatic
lesions (accessory spleen, adrenal masses, duodenal masses, lymph nodes and
vascular lesions), and certain rare pancreatic tumors (e.g., acinar cell tumors,
solid serous tumors, hamartoma and solitary fibrous tumors). The clinical
presentation and imaging features of the most commonly encountered mimics of PDA
are discussed in this presentation with representative illustrations.
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