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Military risk factors for Alzheimer s disease
#MMPMID23809365
Weiner MW
; Friedl KE
; Pacifico A
; Chapman JC
; Jaffee MS
; Little DM
; Manley GT
; McKee A
; Petersen RC
; Pitman RK
; Yaffe K
; Zetterberg H
; Obana R
; Bain LJ
; Carrillo MC
Alzheimers Dement
2013[Jul]; 9
(4
): 445-51
PMID23809365
show ga
Traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) are
signature injuries of the wars in Iraq and Afghanistan and have been linked to an
increased risk of Alzheimer's disease (AD) and other dementias. A meeting hosted
by the Alzheimer's Association and the Veterans' Health Research Institute
(NCIRE) in May 2012 brought together experts from the U.S. military and academic
medical centers around the world to discuss current evidence and hypotheses
regarding the pathophysiological mechanisms linking TBI, PTSD, and AD. Studies
underway in civilian and military populations were highlighted, along with new
research initiatives such as a study to extend the Alzheimer's Disease
Neuroimaging Initiative (ADNI) to a population of veterans exposed to TBI and
PTSD. Greater collaboration and data sharing among diverse research groups is
needed to advance an understanding and appropriate interventions in this
continuum of military injuries and neurodegenerative disease in the aging
veteran.
|*Military Personnel/psychology/statistics & numerical data
[MESH]
|*Veterans Health/statistics & numerical data
[MESH]