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2016 ; 32
(6
): 1057-60
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Microcephaly and Zika virus: neonatal neuroradiological aspects
#MMPMID27080092
Cavalheiro S
; Lopez A
; Serra S
; Da Cunha A
; da Costa MD
; Moron A
; Lederman HM
Childs Nerv Syst
2016[Jun]; 32
(6
): 1057-60
PMID27080092
show ga
PURPOSE: The aim of this study is to describe some radiological features in the
newborns with microcephaly caused by Zika virus infection during pregnancy.
METHODS: We radiologically analyzed 13 cases of newborns with microcephaly born
to mothers who were infected by the Zika virus in the early stage of pregnancy.
RESULTS: The most frequently observed radiological findings were microcephaly and
decreased brain parenchymal volume associated with lissencephaly,
ventriculomegaly secondary to the lack of brain tissue (not hypertensive), and
coarse and anarchic calcifications mainly involving the subcortical cortical
transition, and the basal ganglia. CONCLUSIONS: Although it cannot be concluded
that there is a definitive pathognomonic radiographic pattern of microcephaly
caused by Zika virus, gross calcifications and anarchic distribution involving
the subcortical cortical transition and the basal ganglia, in association with
lissencephaly and in the absence of hypertensive ventriculomegaly, are
characteristic of this type of infection.