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10.1186/s13073-016-0306-z http://scihub22266oqcxt.onion/10.1186/s13073-016-0306-z C4835935!4835935 !27090860     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27090860 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Genome+Med 2016 ; 8 (1 ): 40 Nephropedia Template TP {{tp|p=27090860 |t=2016. Microbiome mediation of infections in the cancer setting |pdf=|usr=}}{{27090860 }} gab.com Text Microbiome mediation of infections in the cancer setting JO: Genome Med http://www.kidney.de/pget.php?&tw=1&pmid=27090860 #FOAvip Infections encountered in the cancer setting may arise from intensive cancer treatments or may result from the cancer itself, leading to risk of infections through immune compromise, disruption of anatomic barriers, and exposure to nosocomial (hospital-acquired) pathogens. Consequently, cancer-related infections are unique and epidemiologically distinct from those in other patient populations and may be particularly challenging for clinicians to treat. There is increasing evidence that the microbiome is a crucial factor in the cancer patient's risk for infectious complications. Frequently encountered pathogens with observed ties to the microbiome include vancomycin-resistant Enterococcus, Enterobacteriaceae, and Clostridium difficile; these organisms can exist in the human body without disease under normal circumstances, but all can arise as infections when the microbiome is disrupted. In the cancer patient, such disruptions may result from interventions such as chemotherapy, broad-spectrum antibiotics, or anatomic alteration through surgery. In this review, we discuss evidence of the significant role of the microbiome in cancer-related infections; how a better understanding of the role of the microbiome can facilitate our understanding of these complications; and how this knowledge might be exploited to improve outcomes in cancer patients and reduce risk of infection. Twit Text FOAVip Microbiome mediation of infections in the cancer setting ????Genome Med http://www.kidney.de/pget.php?&tw=1&pmid=27090860 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27090860 #FOAvip English Wikipedia <ref>{{Cite pmid|27090860 }}</ref> Microbiome mediation of infections in the cancer setting #MMPMID27090860 Taur Y ; Pamer EG Genome Med 2016[Apr]; 8 (1 ): 40 PMID27090860 show ga Infections encountered in the cancer setting may arise from intensive cancer treatments or may result from the cancer itself, leading to risk of infections through immune compromise, disruption of anatomic barriers, and exposure to nosocomial (hospital-acquired) pathogens. Consequently, cancer-related infections are unique and epidemiologically distinct from those in other patient populations and may be particularly challenging for clinicians to treat. There is increasing evidence that the microbiome is a crucial factor in the cancer patient's risk for infectious complications. Frequently encountered pathogens with observed ties to the microbiome include vancomycin-resistant Enterococcus, Enterobacteriaceae, and Clostridium difficile; these organisms can exist in the human body without disease under normal circumstances, but all can arise as infections when the microbiome is disrupted. In the cancer patient, such disruptions may result from interventions such as chemotherapy, broad-spectrum antibiotics, or anatomic alteration through surgery. In this review, we discuss evidence of the significant role of the microbiome in cancer-related infections; how a better understanding of the role of the microbiome can facilitate our understanding of these complications; and how this knowledge might be exploited to improve outcomes in cancer patients and reduce risk of infection. |*Microbiota [MESH] |Anti-Bacterial Agents/pharmacology/therapeutic use [MESH] |Antineoplastic Agents/adverse effects/therapeutic use [MESH] |Gastrointestinal Microbiome [MESH] |Host-Pathogen Interactions [MESH] |Humans [MESH] |Infections/drug therapy/*etiology/microbiology [MESH] |Intestinal Mucosa/drug effects/microbiology/pathology [MESH] |Neoplasms/*complications/therapy [MESH]Microbiome mediation of infections in the cancer setting (epmc).pdf DeepDyve Pubget Overpricing