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10.1093/ndt/gfu280 http://scihub22266oqcxt.onion/10.1093/ndt/gfu280 C4301831!4301831 !25170095     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25170095 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25170095 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nephrol+Dial+Transplant 2015 ; 30 (6 ): 910-7 Nephropedia Template TP {{tp|p=25170095 |t=2015. MicroRNAs in kidney transplantation |pdf=|usr=}}{{25170095 }} gab.com Text MicroRNAs in kidney transplantation JO: Nephrol Dial Transplant http://www.kidney.de/pget.php?&tw=1&pmid=25170095 #FOAvip The discovery of novel classes of non-coding RNAs (ncRNAs) has revolutionized medicine. Long thought to be a mere cellular housekeeper, surprising functions have recently been uncovered. MicroRNAs (miRNAs), are a representative of the class of short ncRNAs, play a fundamental role in the control of DNA and protein biosynthesis and activity as well as pathology. Currently, miRNAs are being investigated as diagnostic and prognostic markers and potential therapeutic targets in kidney transplantation for such indolent processes as ischaemia-reperfusion injury, humoral rejection or viral infections. It is realistic to believe that monitoring of renal allograft recipients in the future will include genome-wide miRNA profiling of biological fluids. Based on these individual profiles, an informed decision on therapeutic consequences will be possible. A first success with a specific suppression of miRNAs by antisense oligonucleotides was achieved in experimental studies of reperfusion injury and humoral rejection. Proof of this concept in men comes from studies in such indolent viral infections as Ebola and hepatitis C, where anti-miR therapy led to sustained viral clearance. In this review, we summarize the basis of the recent ncRNA revolution and its implication for kidney transplantation. Twit Text FOAVip MicroRNAs in kidney transplantation ????Nephrol Dial Transplant http://www.kidney.de/pget.php?&tw=1&pmid=25170095 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25170095 #FOAvip English Wikipedia <ref>{{Cite pmid|25170095 }}</ref> MicroRNAs in kidney transplantation #MMPMID25170095 Wilflingseder J ; Reindl-Schwaighofer R ; Sunzenauer J ; Kainz A ; Heinzel A ; Mayer B ; Oberbauer R Nephrol Dial Transplant 2015[Jun]; 30 (6 ): 910-7 PMID25170095 show ga The discovery of novel classes of non-coding RNAs (ncRNAs) has revolutionized medicine. Long thought to be a mere cellular housekeeper, surprising functions have recently been uncovered. MicroRNAs (miRNAs), are a representative of the class of short ncRNAs, play a fundamental role in the control of DNA and protein biosynthesis and activity as well as pathology. Currently, miRNAs are being investigated as diagnostic and prognostic markers and potential therapeutic targets in kidney transplantation for such indolent processes as ischaemia-reperfusion injury, humoral rejection or viral infections. It is realistic to believe that monitoring of renal allograft recipients in the future will include genome-wide miRNA profiling of biological fluids. Based on these individual profiles, an informed decision on therapeutic consequences will be possible. A first success with a specific suppression of miRNAs by antisense oligonucleotides was achieved in experimental studies of reperfusion injury and humoral rejection. Proof of this concept in men comes from studies in such indolent viral infections as Ebola and hepatitis C, where anti-miR therapy led to sustained viral clearance. In this review, we summarize the basis of the recent ncRNA revolution and its implication for kidney transplantation. |*Kidney Transplantation [MESH] |Biomarkers/*metabolism [MESH] |Humans [MESH] |Kidney Diseases/diagnosis/*genetics/therapy [MESH]MicroRNAs in kidney transplantation (epmc).pdf DeepDyve Pubget Overpricing