Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.18632/oncotarget.14794 http://scihub22266oqcxt.onion/10.18632/oncotarget.14794 C5354711!5354711 !28122334     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28122334 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28122334 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Oncotarget 2017 ; 8 (6 ): 9017-9020 Nephropedia Template TP {{tp|p=28122334 |t=2017. Metformin: a metabolic modulator |pdf=|usr=}}{{28122334 }} gab.com Text Metformin: a metabolic modulator JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28122334 #FOAvip Recent findings have shed new light on the mechanisms of action through which biguanides exert their anti-aging and cytostatic effects in Caenorhabditis elegans and human cell lines. The drop in energy charge resulting from the metformin mediated inhibition of mitochondrial activity affects the function of the nuclear pore complex, blocks mTOR signaling and enhances the expression of ACAD10. Whether the inhibition of this pathway is truly responsible for the anti-diabetic and cancer effects of the drug in mammals remains to be established. Twit Text FOAVip Metformin: a metabolic modulator ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28122334 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28122334 #FOAvip English Wikipedia <ref>{{Cite pmid|28122334 }}</ref> Metformin: a metabolic modulator #MMPMID28122334 Pietrocola F ; Kroemer G Oncotarget 2017[Feb]; 8 (6 ): 9017-9020 PMID28122334 show ga Recent findings have shed new light on the mechanisms of action through which biguanides exert their anti-aging and cytostatic effects in Caenorhabditis elegans and human cell lines. The drop in energy charge resulting from the metformin mediated inhibition of mitochondrial activity affects the function of the nuclear pore complex, blocks mTOR signaling and enhances the expression of ACAD10. Whether the inhibition of this pathway is truly responsible for the anti-diabetic and cancer effects of the drug in mammals remains to be established. |Acyl-CoA Dehydrogenase/metabolism [MESH] |Animals [MESH] |Antineoplastic Agents/*pharmacology [MESH] |Caenorhabditis elegans Proteins/metabolism [MESH] |Caenorhabditis elegans/*drug effects/metabolism [MESH] |Diabetes Mellitus, Type 2/*drug therapy/metabolism [MESH] |Energy Metabolism/*drug effects [MESH] |Humans [MESH] |Hypoglycemic Agents/*pharmacology [MESH] |Metformin/*pharmacology [MESH] |Mitochondria/drug effects/metabolism [MESH] |Neoplasms/*drug therapy/metabolism [MESH] |Signal Transduction/drug effects [MESH]Metformin: a metabolic modulator (epmc).pdf DeepDyve Pubget Overpricing