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10.1016/j.cmet.2016.05.011

http://scihub22266oqcxt.onion/10.1016/j.cmet.2016.05.011
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C5943638!5943638 !27304507
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suck abstract from ncbi


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pmid27304507
      Cell+Metab 2016 ; 23 (6 ): 1060-1065
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  • Metformin as a Tool to Target Aging #MMPMID27304507
  • Barzilai N ; Crandall JP ; Kritchevsky SB ; Espeland MA
  • Cell Metab 2016[Jun]; 23 (6 ): 1060-1065 PMID27304507 show ga
  • Aging has been targeted by genetic and dietary manipulation and by drugs in order to increase lifespan and health span in numerous models. Metformin, which has demonstrated protective effects against several age-related diseases in humans, will be tested in the TAME (Targeting Aging with Metformin) trial, as the initial step in the development of increasingly effective next-generation drugs.
  • |Aging/*drug effects/*physiology [MESH]
  • |Animals [MESH]
  • |Clinical Trials as Topic [MESH]
  • |Humans [MESH]
  • |Longevity/drug effects [MESH]
  • |Metformin/*pharmacology [MESH]
  • |Models, Animal [MESH]


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