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10.1007/s11906-014-0524-y http://scihub22266oqcxt.onion/10.1007/s11906-014-0524-y C4840894!4840894 !25754317     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25754317 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Hypertens+Rep 2015 ; 17 (3 ): 20 Nephropedia Template TP {{tp|p=25754317 |t=2015. Metabolic Dysfunction in Pulmonary Arterial Hypertension |pdf=|usr=}}{{25754317 }} gab.com Text Metabolic Dysfunction in Pulmonary Arterial Hypertension JO: Curr Hypertens Rep http://www.kidney.de/pget.php?&tw=1&pmid=25754317 #FOAvip Previously considered a disease isolated to the pulmonary circulation, pulmonary arterial hypertension is now being recognized as a systemic disorder that is associated with significant metabolic dysfunction. Numerous animal models have demonstrated the development of pulmonary arterial hypertension following the onset of insulin resistance, indicating that insulin resistance may be causal. Recent publications highlighting alterations in aerobic glycolysis, fatty acid oxidation, and the tricarboxylic acid cycle in the pulmonary circulation and right ventricle have expanded our understanding of the complex pathobiology of this disease. By targeting these derangements in metabolism, numerous researchers are investigating noninvasive techniques to monitor disease activity and therapeutics that address the underlying metabolic condition. In the following review, we will explore pre-clinical and clinical studies investigating the metabolic dysfunction seen in pulmonary arterial hypertension. Twit Text FOAVip Metabolic Dysfunction in Pulmonary Arterial Hypertension ????Curr Hypertens Rep http://www.kidney.de/pget.php?&tw=1&pmid=25754317 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25754317 #FOAvip English Wikipedia <ref>{{Cite pmid|25754317 }}</ref> Metabolic Dysfunction in Pulmonary Arterial Hypertension #MMPMID25754317 Assad TR ; Hemnes AR Curr Hypertens Rep 2015[Mar]; 17 (3 ): 20 PMID25754317 show ga Previously considered a disease isolated to the pulmonary circulation, pulmonary arterial hypertension is now being recognized as a systemic disorder that is associated with significant metabolic dysfunction. Numerous animal models have demonstrated the development of pulmonary arterial hypertension following the onset of insulin resistance, indicating that insulin resistance may be causal. Recent publications highlighting alterations in aerobic glycolysis, fatty acid oxidation, and the tricarboxylic acid cycle in the pulmonary circulation and right ventricle have expanded our understanding of the complex pathobiology of this disease. By targeting these derangements in metabolism, numerous researchers are investigating noninvasive techniques to monitor disease activity and therapeutics that address the underlying metabolic condition. In the following review, we will explore pre-clinical and clinical studies investigating the metabolic dysfunction seen in pulmonary arterial hypertension. |*Hypertension, Pulmonary/etiology/genetics/physiopathology [MESH] |Aerobiosis [MESH] |Animals [MESH] |Glycolysis [MESH] |Humans [MESH] |Insulin Resistance [MESH] |Metabolic Syndrome/*complications [MESH] |Oxidation-Reduction [MESH]Metabolic Dysfunction in Pulmonary Arterial Hypertension (epmc).pdf DeepDyve Pubget Overpricing