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2018 ; 16
(1
): 78
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Meningeal carcinomatosis: three case-reports
#MMPMID29653576
Chen G
; Ma L
; Xu M
; Wang X
; Wang C
; Zhao C
; Zhang J
World J Surg Oncol
2018[Apr]; 16
(1
): 78
PMID29653576
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BACKGROUND: Meningeal carcinomatosis (MC) is characterized by diffuse
infiltration of tumor cells in meninges. There is no tumor mass in the brain and
parenchyma of the spinal cord. MC is divided into primary and metastatic types.
MC cases were previously diagnosed postoperatively or at autopsy. Recent advances
in spinal abbreviation cytology and imaging have led to increase in number of
reported cases. In this study, we discuss the manifestations of MC patients based
on magnetic resonance imaging (MRI) findings, as well as the correlation between
the manifestations and pathology. CASE PRESENTATION: MC was confirmed in all
three cases by lumbar puncture and gadopentetate dimeglumine-enhanced magnetic
resonance imaging. Due to different primary diseases, the patients had specific
imaging manifestations. CONCLUSION: Enhanced MRI examination is extremely
sensitive for detecting abnormalities in meninges, which plays a very important
role in the diagnosis of MC. Since meninges of some MC patients cannot be
enhanced, the enhanced MRI examination cannot be replaced by conventional
cerebrospinal abbreviation examination. Attribute to the diversity of MR contrast
agents, which could provide higher lesion conspicuity and enhances lesion
detection, there may be some more choices to improve the detection rate of MC
patients and prolong their survival lifetime.
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