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Neuron
2017[Jul]; 95
(2
): 259-279
PMID28728021
show ga
Memory is an adaptation to particular temporal properties of past events, such as
the frequency of occurrence of a stimulus or the coincidence of multiple stimuli.
In neurons, this adaptation can be understood in terms of a hierarchical system
of molecular and cellular time windows, which collectively retain information
from the past. We propose that this system makes various timescales of past
experience simultaneously available for future adjustment of behavior. More
generally, we propose that the ability to detect and respond to temporally
structured information underlies the nervous system's capacity to encode and
store a memory at molecular, cellular, synaptic, and circuit levels.
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