Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1371/journal.pone.0150004 http://scihub22266oqcxt.onion/10.1371/journal.pone.0150004 C4773234!4773234 !26930466     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26930466 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       PLoS+One 2016 ; 11 (3 ): e0150004 Nephropedia Template TP {{tp|p=26930466 |t=2016. Membrane Blebbing Is Required for Mesenchymal Precursor Migration |pdf=|usr=}}{{26930466 }} gab.com Text Membrane Blebbing Is Required for Mesenchymal Precursor Migration JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26930466 #FOAvip Mesenchymal precursors (MPs) present some advantageous features, such as differentiation and migration, which make them promising candidates for cell therapy. A better understanding of MP migration characteristics would aid the development of cell delivery protocols. Traditionally, cell migration is thought to occur only through the formation of lamellipodia. More recently, contractility-driven bleb formation has emerged as an alternative mechanism of motility. Here we report that MPs derived from different tissues present spontaneously dynamic cytoplasmic projections in sub-confluent culture, which appear as a combination of lamellipodia with blebs in the leading edge. Upon initial seeding, however, only bleb structures could be observed. Immunofluorescence revealed the presence of pERM, RhoA and F-actin during the blebbing process. Results from migration assays in the presence of blebbistatin, a myosin II inhibitor, showed that bleb formation correlated with migratory capacity, suggesting a functional role for blebs in migration. Bleb formation might be a useful mechanism to improve cell migration in cellular therapy protocols. Twit Text FOAVip Membrane Blebbing Is Required for Mesenchymal Precursor Migration ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26930466 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26930466 #FOAvip English Wikipedia <ref>{{Cite pmid|26930466 }}</ref> Membrane Blebbing Is Required for Mesenchymal Precursor Migration #MMPMID26930466 de Lucas B ; Bernal A ; Pérez LM ; San Martín N ; Gálvez BG PLoS One 2016[]; 11 (3 ): e0150004 PMID26930466 show ga Mesenchymal precursors (MPs) present some advantageous features, such as differentiation and migration, which make them promising candidates for cell therapy. A better understanding of MP migration characteristics would aid the development of cell delivery protocols. Traditionally, cell migration is thought to occur only through the formation of lamellipodia. More recently, contractility-driven bleb formation has emerged as an alternative mechanism of motility. Here we report that MPs derived from different tissues present spontaneously dynamic cytoplasmic projections in sub-confluent culture, which appear as a combination of lamellipodia with blebs in the leading edge. Upon initial seeding, however, only bleb structures could be observed. Immunofluorescence revealed the presence of pERM, RhoA and F-actin during the blebbing process. Results from migration assays in the presence of blebbistatin, a myosin II inhibitor, showed that bleb formation correlated with migratory capacity, suggesting a functional role for blebs in migration. Bleb formation might be a useful mechanism to improve cell migration in cellular therapy protocols. |Actin Cytoskeleton/metabolism [MESH] |Actins/metabolism [MESH] |Animals [MESH] |Cell Differentiation/drug effects/physiology [MESH] |Cell Membrane/drug effects/*metabolism [MESH] |Cell Movement/drug effects/*physiology [MESH] |Heterocyclic Compounds, 4 or More Rings/pharmacology [MESH] |Mesenchymal Stem Cells/*cytology/drug effects/metabolism [MESH] |Mice [MESH] |Pseudopodia/metabolism [MESH]Membrane Blebbing Is Required for Mesenchymal Precursor Migration (epmc).pdf DeepDyve Pubget Overpricing