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Melorheostosis - Case Report of Rare Disease
#MMPMID27298954
Kumar R
; Sankhala SS
; Bijarnia I
J Orthop Case Rep
2014[Apr]; 4
(2
): 25-7
PMID27298954
show ga
INTRODUCTION: Melorheostosis(synonyms: candle bone disease, melting wax syndrome,
Leri disease) is a rare chronic bone disorder, first described in 1922 by Leri
and Joanny. Men and women are equally affected, and no hereditary features have
been discovered. Onset is insidious, and most common symptom is pain. Most common
part of bone is diaphysis of the long bone of lower limb rarely the axial
skeleton. Classical radiological appearance of 'flowing hyperosteosis' resembling
hardened wax that has dripped down the side of a candle. CASE REPORT: A 35 years
old woman presented with left leg pain with mild swelling and limitation of knee
movement. On examination non tender bony heard swelling, hyperpigmented and
restriction of knee movement present. Plain radiographs showed extensive, dense,
undulating or irregular cortical hyperostosis, resembling candle wax, extending
along the length of bone. Pamidronate as well asanalgesic were given to the
patient. Physiotherepy started for the deformity. CONCLUSION: Routine laboratory
findings usually are normal. The exact cause remain unclear. There is no definite
treatment available for this disease. Only symptomatic treatment improve the
condition of the patients, more fruitful result obtain with pamidronate and
physiotherapy.
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