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2015 ; 7
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Meiosis: an overview of key differences from mitosis
#MMPMID25605710
Ohkura H
Cold Spring Harb Perspect Biol
2015[Jan]; 7
(5
): ä PMID25605710
show ga
Meiosis is the specialized cell division that generates gametes. In contrast to
mitosis, molecular mechanisms and regulation of meiosis are much less understood.
Meiosis shares mechanisms and regulation with mitosis in many aspects, but also
has critical differences from mitosis. This review highlights these differences
between meiosis and mitosis. Recent studies using various model systems revealed
differences in a surprisingly wide range of aspects, including cell-cycle
regulation, recombination, postrecombination events, spindle assembly,
chromosome-spindle interaction, and chromosome segregation. Although a great
degree of diversity can be found among organisms, meiosis-specific processes, and
regulation are generally conserved.