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10.1080/19491034.2017.1371398 http://scihub22266oqcxt.onion/10.1080/19491034.2017.1371398 C5973258!5973258 !29099288     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29099288 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Nucleus 2018 ; 9 (1 ): 9-19 Nephropedia Template TP {{tp|p=29099288 |t=2018. Mechano-adaptation of the stem cell nucleus |pdf=|usr=}}{{29099288 }} gab.com Text Mechano-adaptation of the stem cell nucleus JO: Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=29099288 #FOAvip Exogenous mechanical forces are transmitted through the cell and to the nucleus, initiating mechanotransductive signaling cascades with profound effects on cellular function and stem cell fate. A growing body of evidence has shown that the force sensing and force-responsive elements of the nucleus adapt to these mechanotransductive events, tuning their response to future mechanical input. The mechanisms underlying this "mechano-adaptation" are only just beginning to be elucidated, and it remains poorly understood how these components act and adapt in tandem to drive stem cell differentiation. Here, we review the evidence on how the stem cell nucleus responds and adapts to physical forces, and provide a perspective on how this mechano-adaptation may function to drive and enforce stem cell differentiation. Twit Text FOAVip Mechano-adaptation of the stem cell nucleus ????Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=29099288 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29099288 #FOAvip English Wikipedia <ref>{{Cite pmid|29099288 }}</ref> Mechano-adaptation of the stem cell nucleus #MMPMID29099288 Heo SJ ; Cosgrove BD ; Dai EN ; Mauck RL Nucleus 2018[Jan]; 9 (1 ): 9-19 PMID29099288 show ga Exogenous mechanical forces are transmitted through the cell and to the nucleus, initiating mechanotransductive signaling cascades with profound effects on cellular function and stem cell fate. A growing body of evidence has shown that the force sensing and force-responsive elements of the nucleus adapt to these mechanotransductive events, tuning their response to future mechanical input. The mechanisms underlying this "mechano-adaptation" are only just beginning to be elucidated, and it remains poorly understood how these components act and adapt in tandem to drive stem cell differentiation. Here, we review the evidence on how the stem cell nucleus responds and adapts to physical forces, and provide a perspective on how this mechano-adaptation may function to drive and enforce stem cell differentiation. |Adaptation, Physiological [MESH] |Animals [MESH] |Cell Differentiation [MESH] |Cell Nucleus/*metabolism [MESH] |Humans [MESH] |Mechanical Phenomena [MESH]Mechano-adaptation of the stem cell nucleus (epmc).pdf DeepDyve Pubget Overpricing