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10.1172/JCI78088 http://scihub22266oqcxt.onion/10.1172/JCI78088 C4518692!4518692 !25893595     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25893595 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Clin+Invest 2015 ; 125 (6 ): 2228-33 Nephropedia Template TP {{tp|p=25893595 |t=2015. Mechanisms of human autoimmunity |pdf=|usr=}}{{25893595 }} gab.com Text Mechanisms of human autoimmunity JO: J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=25893595 #FOAvip Autoimmune reactions reflect an imbalance between effector and regulatory immune responses, typically develop through stages of initiation and propagation, and often show phases of resolution (indicated by clinical remissions) and exacerbations (indicated by symptomatic flares). The fundamental underlying mechanism of autoimmunity is defective elimination and/or control of self-reactive lymphocytes. Studies in humans and experimental animal models are revealing the genetic and environmental factors that contribute to autoimmunity. A major goal of research in this area is to exploit this knowledge to better understand the pathogenesis of autoimmune diseases and to develop strategies for reestablishing the normal balance between effector and regulatory immune responses. Twit Text FOAVip Mechanisms of human autoimmunity ????J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=25893595 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25893595 #FOAvip English Wikipedia <ref>{{Cite pmid|25893595 }}</ref> Mechanisms of human autoimmunity #MMPMID25893595 Rosenblum MD ; Remedios KA ; Abbas AK J Clin Invest 2015[Jun]; 125 (6 ): 2228-33 PMID25893595 show ga Autoimmune reactions reflect an imbalance between effector and regulatory immune responses, typically develop through stages of initiation and propagation, and often show phases of resolution (indicated by clinical remissions) and exacerbations (indicated by symptomatic flares). The fundamental underlying mechanism of autoimmunity is defective elimination and/or control of self-reactive lymphocytes. Studies in humans and experimental animal models are revealing the genetic and environmental factors that contribute to autoimmunity. A major goal of research in this area is to exploit this knowledge to better understand the pathogenesis of autoimmune diseases and to develop strategies for reestablishing the normal balance between effector and regulatory immune responses. |*Autoimmunity [MESH] |Animals [MESH] |Autoimmune Diseases/*immunology/pathology [MESH] |Environmental Exposure/*adverse effects [MESH] |Humans [MESH]Mechanisms of human autoimmunity (epmc).pdf DeepDyve Pubget Overpricing