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10.1016/j.orcp.2013.12.005 http://scihub22266oqcxt.onion/10.1016/j.orcp.2013.12.005 C4250935!4250935 !25434909     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25434909 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25434909 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Obes+Res+Clin+Pract 2014 ; 8 (6 ): e540-8 Nephropedia Template TP {{tp|p=25434909 |t=2014. Mechanisms of heart failure in obesity |pdf=|usr=}}{{25434909 }} gab.com Text Mechanisms of heart failure in obesity JO: Obes Res Clin Pract http://www.kidney.de/pget.php?&tw=1&pmid=25434909 #FOAvip Heart failure is a leading cause of morbidity and mortality and its prevalence continues to rise. Because obesity has been linked with heart failure, the increasing prevalence of obesity may presage further rise in heart failure in the future. Obesity-related factors are estimated to cause 11% of heart failure cases in men and 14% in women. Obesity may result in heart failure by inducing haemodynamic and myocardial changes that lead to cardiac dysfunction, or due to an increased predisposition to other heart failure risk factors. Direct cardiac lipotoxicity has been described where lipid accumulation in the heart results in cardiac dysfunction inexplicable of other heart failure risk factors. In this overview, we discussed various pathophysiological mechanisms that could lead to heart failure in obesity, including the molecular mechanisms underlying cardiac lipotoxicity. We defined the obesity paradox and enumerated various premises for the paradoxical associations observed in the relationship between obesity and heart failure. Twit Text FOAVip Mechanisms of heart failure in obesity ????Obes Res Clin Pract http://www.kidney.de/pget.php?&tw=1&pmid=25434909 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25434909 #FOAvip English Wikipedia <ref>{{Cite pmid|25434909 }}</ref> Mechanisms of heart failure in obesity #MMPMID25434909 Ebong IA ; Goff DC Jr ; Rodriguez CJ ; Chen H ; Bertoni AG Obes Res Clin Pract 2014[Nov]; 8 (6 ): e540-8 PMID25434909 show ga Heart failure is a leading cause of morbidity and mortality and its prevalence continues to rise. Because obesity has been linked with heart failure, the increasing prevalence of obesity may presage further rise in heart failure in the future. Obesity-related factors are estimated to cause 11% of heart failure cases in men and 14% in women. Obesity may result in heart failure by inducing haemodynamic and myocardial changes that lead to cardiac dysfunction, or due to an increased predisposition to other heart failure risk factors. Direct cardiac lipotoxicity has been described where lipid accumulation in the heart results in cardiac dysfunction inexplicable of other heart failure risk factors. In this overview, we discussed various pathophysiological mechanisms that could lead to heart failure in obesity, including the molecular mechanisms underlying cardiac lipotoxicity. We defined the obesity paradox and enumerated various premises for the paradoxical associations observed in the relationship between obesity and heart failure. |Body Mass Index [MESH] |Female [MESH] |Heart Failure/*etiology/physiopathology [MESH] |Humans [MESH] |Lipids/adverse effects [MESH] |Male [MESH]Mechanisms of heart failure in obesity (epmc).pdf DeepDyve Pubget Overpricing