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10.3389/fimmu.2018.00855 http://scihub22266oqcxt.onion/10.3389/fimmu.2018.00855 C5936990!5936990 !29760698     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29760698 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Front+Immunol 2018 ; 9 (ä): 855 Nephropedia Template TP {{tp|p=29760698 |t=2018. Mechanisms of Cryptococcus neoformans-Mediated Host Damage |pdf=|usr=}}{{29760698 }} gab.com Text Mechanisms of Cryptococcus neoformans-Mediated Host Damage JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29760698 #FOAvip Cryptococcus neoformans is not usually considered a cytotoxic fungal pathogen but there is considerable evidence that this microbe can damage host cells and tissues. In this essay, we review the evidence that C. neoformans damages host cells and note that the mechanisms involved are diverse. We consider C. neoformans-mediated host damage at the molecular, cellular, tissue, and organism level. Direct mechanisms of cytotoxicity include lytic exocytosis, organelle dysfunction, phagolysosomal membrane damage, and cytoskeletal alterations. Cytotoxicity contributes to pathogenesis by interfering with immune effector cell function and disrupting endothelial barriers thus allowing dissemination. When C. neoformans-mediated and immune-mediated host damage is sufficient to affect homeostasis, cryptococcosis occurs at the organism level. Twit Text FOAVip Mechanisms of Cryptococcus neoformans-Mediated Host Damage ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29760698 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29760698 #FOAvip English Wikipedia <ref>{{Cite pmid|29760698 }}</ref> Mechanisms of Cryptococcus neoformans-Mediated Host Damage #MMPMID29760698 Casadevall A ; Coelho C ; Alanio A Front Immunol 2018[]; 9 (ä): 855 PMID29760698 show ga Cryptococcus neoformans is not usually considered a cytotoxic fungal pathogen but there is considerable evidence that this microbe can damage host cells and tissues. In this essay, we review the evidence that C. neoformans damages host cells and note that the mechanisms involved are diverse. We consider C. neoformans-mediated host damage at the molecular, cellular, tissue, and organism level. Direct mechanisms of cytotoxicity include lytic exocytosis, organelle dysfunction, phagolysosomal membrane damage, and cytoskeletal alterations. Cytotoxicity contributes to pathogenesis by interfering with immune effector cell function and disrupting endothelial barriers thus allowing dissemination. When C. neoformans-mediated and immune-mediated host damage is sufficient to affect homeostasis, cryptococcosis occurs at the organism level. |Animals [MESH] |Cryptococcosis/*immunology [MESH] |Cryptococcus neoformans/*immunology [MESH] |Host-Pathogen Interactions/*immunology [MESH] |Humans [MESH]Mechanisms of Cryptococcus neoformans-Mediated Host Damage (epmc).pdf DeepDyve Pubget Overpricing