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2017 ; 10
(ä): 1561-1573
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Mechanism of immune evasion in breast cancer
#MMPMID28352189
Wang M
; Zhang C
; Song Y
; Wang Z
; Wang Y
; Luo F
; Xu Y
; Zhao Y
; Wu Z
; Xu Y
Onco Targets Ther
2017[]; 10
(ä): 1561-1573
PMID28352189
show ga
Breast cancer (BC) is the most common malignant tumor among women, with high
morbidity and mortality. Its onset, development, metastasis, and prognosis vary
among individuals due to the interactions between tumors and host immunity. Many
diverse mechanisms have been associated with BC, with immune evasion being the
most widely studied to date. Tumor cells can escape from the body's immune
response, which targets abnormal components and foreign bodies, using different
approaches including modification of surface antigens and modulation of the
surrounding environment. In this review, we summarize the mechanisms and factors
that impact the immunoediting process and analyze their functions in detail.