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10.1016/j.ceb.2016.04.006

http://scihub22266oqcxt.onion/10.1016/j.ceb.2016.04.006
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C5428743!5428743 !27131272
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suck abstract from ncbi


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pmid27131272
      Curr+Opin+Cell+Biol 2016 ; 42 (ä): 52-62
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  • Mechanics of epithelial tissues during gap closure #MMPMID27131272
  • Begnaud S ; Chen T ; Delacour D ; Mège RM ; Ladoux B
  • Curr Opin Cell Biol 2016[Oct]; 42 (ä): 52-62 PMID27131272 show ga
  • The closure of gaps is crucial to maintaining epithelium integrity during developmental and repair processes such as dorsal closure and wound healing. Depending on biochemical as well as physical properties of the microenvironment, gap closure occurs through assembly of multicellular actin-based contractile cables and/or protrusive activity of cells lining the gap. This review discusses the relative contributions of 'purse-string' and cell crawling mechanisms regulated by cell-substrate and cell-cell interactions, cellular mechanics and physical constraints from the environment.
  • |*Body Patterning [MESH]
  • |Actins [MESH]
  • |Actomyosin/metabolism [MESH]
  • |Animals [MESH]
  • |Biomechanical Phenomena [MESH]
  • |Epithelial Cells/cytology/metabolism [MESH]
  • |Epithelium/*physiology [MESH]


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