Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26045965
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26045965
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Intensive+Care
2015 ; 3
(1
): 25
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Mechanical ventilation of acute respiratory distress syndrome
#MMPMID26045965
Ochiai R
J Intensive Care
2015[]; 3
(1
): 25
PMID26045965
show ga
Acute respiratory distress syndrome (ARDS) has been intensively and continuously
studied in various settings, but its mortality is still as high as 30-40 %. For
the last 20 years, lung protective strategy has become a standard care for ARDS,
but we still do not know the best way to ventilate patients with ARDS. Tidal
volume itself does not seem to have an important role to develop
ventilator-induced lung injury (VILI), but the driving pressure, which is
inspiratory plateau pressure-PEEP, is the most important to predict and affect
the outcome of ARDS, though there is no safe limit for the driving pressure.
There is so much controversy regarding what the best PEEP is, whether collapsed
lung should be recruited, and what parameters should be measured and evaluated to
improve the outcome of ARDS. Since the mechanical ventilation for patients with
respiratory failure, including ARDS, is a standard care, we need more dynamic and
regional information of ventilation and pulmonary circulation in the injured
lungs to evaluate the efficacy of new type of treatment strategy. In addition to
the CT scanning of the lung as the gold standard of evaluation, the electrical
impedance tomography (EIT) of the lung has been clinically available to provide
such information non-invasively and at the bedside. Various parameters have been
tested to evaluate the homogeneity of regional ventilation, and EIT could provide
us with the information of ventilator settings to minimize VILI.