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10.1165/rcmb.2015-0166PS http://scihub22266oqcxt.onion/10.1165/rcmb.2015-0166PS C4942216!4942216 !26741177     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26741177 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Am+J+Respir+Cell+Mol+Biol 2016 ; 54 (6 ): 751-60 Nephropedia Template TP {{tp|p=26741177 |t=2016. Matrix Remodeling in Pulmonary Fibrosis and Emphysema |pdf=|usr=}}{{26741177 }} gab.com Text Matrix Remodeling in Pulmonary Fibrosis and Emphysema JO: Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=26741177 #FOAvip Pulmonary fibrosis and emphysema are chronic lung diseases characterized by a progressive decline in lung function, resulting in significant morbidity and mortality. A hallmark of these diseases is recurrent or persistent alveolar epithelial injury, typically caused by common environmental exposures such as cigarette smoke. We propose that critical determinants of the outcome of the injury-repair processes that result in fibrosis versus emphysema are mesenchymal cell fate and associated extracellular matrix dynamics. In this review, we explore the concept that regulation of mesenchymal cells under the influence of soluble factors, in particular transforming growth factor-?1, and the extracellular matrix determine the divergent tissue remodeling responses seen in pulmonary fibrosis and emphysema. Twit Text FOAVip Matrix Remodeling in Pulmonary Fibrosis and Emphysema ????Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=26741177 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26741177 #FOAvip English Wikipedia <ref>{{Cite pmid|26741177 }}</ref> Matrix Remodeling in Pulmonary Fibrosis and Emphysema #MMPMID26741177 Kulkarni T ; O'Reilly P ; Antony VB ; Gaggar A ; Thannickal VJ Am J Respir Cell Mol Biol 2016[Jun]; 54 (6 ): 751-60 PMID26741177 show ga Pulmonary fibrosis and emphysema are chronic lung diseases characterized by a progressive decline in lung function, resulting in significant morbidity and mortality. A hallmark of these diseases is recurrent or persistent alveolar epithelial injury, typically caused by common environmental exposures such as cigarette smoke. We propose that critical determinants of the outcome of the injury-repair processes that result in fibrosis versus emphysema are mesenchymal cell fate and associated extracellular matrix dynamics. In this review, we explore the concept that regulation of mesenchymal cells under the influence of soluble factors, in particular transforming growth factor-?1, and the extracellular matrix determine the divergent tissue remodeling responses seen in pulmonary fibrosis and emphysema. |Animals [MESH] |Extracellular Matrix/*metabolism [MESH] |Fibroblasts/pathology [MESH] |Humans [MESH] |Lung Injury/complications/pathology [MESH] |Pulmonary Emphysema/*complications/*metabolism [MESH] |Pulmonary Fibrosis/*complications/*metabolism [MESH]Matrix Remodeling in Pulmonary Fibrosis and Emphysema (epmc).pdf DeepDyve Pubget Overpricing