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10.1001/archneurol.2011.2506 http://scihub22266oqcxt.onion/10.1001/archneurol.2011.2506 C4776649!4776649 !22689191     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\22689191 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Arch+Neurol 2012 ; 69 (6 ): 693-9 Nephropedia Template TP {{tp|p=22689191 |t=2012. Maternal autoantibodies in autism |pdf=|usr=}}{{22689191 }} gab.com Text Maternal autoantibodies in autism JO: Arch Neurol http://www.kidney.de/pget.php?&tw=1&pmid=22689191 #FOAvip As epidemiologic studies continue to note a striking increase in rates of autism spectrum disorder (ASD) diagnosis around the world, the lack of identified causative agents in most cases remains a major hindrance to the development of treatment and prevention strategies. Published observations of immune system abnormalities in ASD have increased recently, with several groups identifying fetal protein reactive IgG antibodies in plasma from mothers of children with autism. Furthermore, other gestational immune parameters, including maternal infection and dysregulated cytokine signaling, have been found to be associated with ASD in some cases. While detailed pathogenic mechanisms remain to be determined, the hypothesis that some cases of ASD may be influenced, or even caused, by maternal fetal brain-reactive antibodies or other in utero immune-related exposures is an active area of investigation. This article reviews the current literature in this area and proposes several directions for future research. Twit Text FOAVip Maternal autoantibodies in autism ????Arch Neurol http://www.kidney.de/pget.php?&tw=1&pmid=22689191 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22689191 #FOAvip English Wikipedia <ref>{{Cite pmid|22689191 }}</ref> Maternal autoantibodies in autism #MMPMID22689191 Braunschweig D ; Van de Water J Arch Neurol 2012[Jun]; 69 (6 ): 693-9 PMID22689191 show ga As epidemiologic studies continue to note a striking increase in rates of autism spectrum disorder (ASD) diagnosis around the world, the lack of identified causative agents in most cases remains a major hindrance to the development of treatment and prevention strategies. Published observations of immune system abnormalities in ASD have increased recently, with several groups identifying fetal protein reactive IgG antibodies in plasma from mothers of children with autism. Furthermore, other gestational immune parameters, including maternal infection and dysregulated cytokine signaling, have been found to be associated with ASD in some cases. While detailed pathogenic mechanisms remain to be determined, the hypothesis that some cases of ASD may be influenced, or even caused, by maternal fetal brain-reactive antibodies or other in utero immune-related exposures is an active area of investigation. This article reviews the current literature in this area and proposes several directions for future research. |*Autistic Disorder/diagnosis/etiology/immunology [MESH] |Autoantibodies/*blood/immunology [MESH] |Female [MESH] |Fetal Proteins/*immunology [MESH] |Humans [MESH] |Male [MESH] |Maternal-Fetal Exchange/*immunology [MESH]Maternal autoantibodies in autism (epmc).pdf DeepDyve Pubget Overpricing