Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27153492
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Cell
2016 ; 165
(4
): 780-91
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Mass Cytometry: Single Cells, Many Features
#MMPMID27153492
Spitzer MH
; Nolan GP
Cell
2016[May]; 165
(4
): 780-91
PMID27153492
show ga
Technology development in biological research often aims to either increase the
number of cellular features that can be surveyed simultaneously or enhance the
resolution at which such observations are possible. For decades, flow cytometry
has balanced these goals to fill a critical need by enabling the measurement of
multiple features in single cells, commonly to examine complex or hierarchical
cellular systems. Recently, a format for flow cytometry has been developed that
leverages the precision of mass spectrometry. This fusion of the two
technologies, termed mass cytometry, provides measurement of over 40 simultaneous
cellular parameters at single-cell resolution, significantly augmenting the
ability of cytometry to evaluate complex cellular systems and processes. In this
Primer, we review the current state of mass cytometry, providing an overview of
the instrumentation, its present capabilities, and methods of data analysis, as
well as thoughts on future developments and applications.
free
free
free
