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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Pharm+Bioallied+Sci
2017 ; 9
(1
): 73-77
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Marfan Syndrome
#MMPMID28584496
Sivasankari T
; Mathew P
; Austin RD
; Devi S
J Pharm Bioallied Sci
2017[Jan]; 9
(1
): 73-77
PMID28584496
show ga
Marfan syndrome (MFS) is the autosomal dominant-inherited multisystem
connective-tissue disorder, with a reported incidence of 1 in 10,000 individuals
and equal distribution in both genders. The main clinical manifestation of this
disorder consists of an exaggerated length of the upper and lower limbs,
hyperlaxity, scoliosis, alterations in the cardiovascular and pulmonary systems,
and atypical bone overgrowth. Orofacial manifestations such as high-arched
palate, hypodontia, long narrow teeth, bifid uvula, mandibular prognathism, and
temporomandibular disorders are also common. Early diagnosis of MFS is essential
to prevent the cardiovascular complications and treatment of orofacial
manifestations, thus to increase the quality of life of the patient.