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10.1016/j.gde.2013.10.014

http://scihub22266oqcxt.onion/10.1016/j.gde.2013.10.014
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C4035372!4035372 !24584091
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suck abstract from ncbi

pmid24584091
      Curr+Opin+Genet+Dev 2014 ; 25 (?): 1-7
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  • Manipulating nuclear architecture #MMPMID24584091
  • Deng W ; Blobel GA
  • Curr Opin Genet Dev 2014[Apr]; 25 (?): 1-7 PMID24584091 show ga
  • The eukaryotic genome is highly organized in the nucleus. Genes can be localized to specific nuclear compartments in a manner reflecting their activity. A plethora of recent reports has described multiple levels of chromosomal folding that can be related to gene-specific expression states. Here we discuss studies designed to probe the causal impact of genome organization on gene expression. The picture that emerges is that of a reciprocal relationship in which nuclear organization is not only shaped by gene expression states but also directly influences them.
  • |Animals [MESH]
  • |Cell Nucleus/*genetics [MESH]
  • |Chromatin/chemistry/*genetics [MESH]
  • |Gene Expression [MESH]
  • |Genome [MESH]


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