Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25740698
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Making animals alcoholic: shifting laboratory models of addiction
#MMPMID25740698
Ramsden E
J Hist Behav Sci
2015[Spr]; 51
(2
): 164-94
PMID25740698
show ga
The use of animals as experimental organisms has been critical to the development
of addiction research from the nineteenth century. They have been used as a means
of generating reliable data regarding the processes of addiction that was not
available from the study of human subjects. Their use, however, has been far from
straightforward. Through focusing on the study of alcoholism, where the nonhuman
animal proved a most reluctant collaborator, this paper will analyze the ways in
which scientists attempted to deal with its determined sobriety and account for
their consistent failure to replicate the volitional consumption of ethanol to
the point of physical dependency. In doing so, we will see how the animal model
not only served as a means of interrogating a complex pathology, but also came to
embody competing definitions of alcoholism as a disease process, and alternative
visions for the very structure and purpose of a research field.
free
free
free
