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10.1155/2015/571893 http://scihub22266oqcxt.onion/10.1155/2015/571893 C4465740!4465740 !26113865     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26113865 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Stem+Cells+Int 2015 ; 2015 (ä): 571893 Nephropedia Template TP {{tp|p=26113865 |t=2015. Making Blood: The Haematopoietic Niche throughout Ontogeny |pdf=|usr=}}{{26113865 }} gab.com Text Making Blood: The Haematopoietic Niche throughout Ontogeny JO: Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=26113865 #FOAvip Approximately one-quarter of all cells in the adult human body are blood cells. The haematopoietic system is therefore massive in scale and requires exquisite regulation to be maintained under homeostatic conditions. It must also be able to respond when needed, such as during infection or following blood loss, to produce more blood cells. Supporting cells serve to maintain haematopoietic stem and progenitor cells during homeostatic and pathological conditions. This coalition of supportive cell types, organised in specific tissues, is termed the haematopoietic niche. Haematopoietic stem and progenitor cells are generated in a number of distinct locations during mammalian embryogenesis. These stem and progenitor cells migrate to a variety of anatomical locations through the conceptus until finally homing to the bone marrow shortly before birth. Under stress, extramedullary haematopoiesis can take place in regions that are typically lacking in blood-producing activity. Our aim in this review is to examine blood production throughout the embryo and adult, under normal and pathological conditions, to identify commonalities and distinctions between each niche. A clearer understanding of the mechanism underlying each haematopoietic niche can be applied to improving ex vivo cultures of haematopoietic stem cells and potentially lead to new directions for transplantation medicine. Twit Text FOAVip Making Blood: The Haematopoietic Niche throughout Ontogeny ????Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=26113865 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26113865 #FOAvip English Wikipedia <ref>{{Cite pmid|26113865 }}</ref> Making Blood: The Haematopoietic Niche throughout Ontogeny #MMPMID26113865 Al-Drees MA ; Yeo JH ; Boumelhem BB ; Antas VI ; Brigden KW ; Colonne CK ; Fraser ST Stem Cells Int 2015[]; 2015 (ä): 571893 PMID26113865 show ga Approximately one-quarter of all cells in the adult human body are blood cells. The haematopoietic system is therefore massive in scale and requires exquisite regulation to be maintained under homeostatic conditions. It must also be able to respond when needed, such as during infection or following blood loss, to produce more blood cells. Supporting cells serve to maintain haematopoietic stem and progenitor cells during homeostatic and pathological conditions. This coalition of supportive cell types, organised in specific tissues, is termed the haematopoietic niche. Haematopoietic stem and progenitor cells are generated in a number of distinct locations during mammalian embryogenesis. These stem and progenitor cells migrate to a variety of anatomical locations through the conceptus until finally homing to the bone marrow shortly before birth. Under stress, extramedullary haematopoiesis can take place in regions that are typically lacking in blood-producing activity. Our aim in this review is to examine blood production throughout the embryo and adult, under normal and pathological conditions, to identify commonalities and distinctions between each niche. A clearer understanding of the mechanism underlying each haematopoietic niche can be applied to improving ex vivo cultures of haematopoietic stem cells and potentially lead to new directions for transplantation medicine. äMaking Blood: The Haematopoietic Niche throughout Ontogeny (epmc).pdf DeepDyve Pubget Overpricing