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2015 ; 11
(4
): 176-81
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Major bioactive metabolites from marine fungi: A Review
#MMPMID26124556
Hasan S
; Ansari MI
; Ahmad A
; Mishra M
Bioinformation
2015[]; 11
(4
): 176-81
PMID26124556
show ga
Biologists and chemists of the world have been attracted towards marine natural
products for the last five decades. Approximately 16,000 marine natural products
have been isolated from marine organisms which have been reported in
approximately 6,800 publications, proving marine microorganisms to be a
invaluable source for the production of novel antibiotic, anti tumor, and anti
inflammatory agents. The marine fungi particularly those associated with marine
alga, sponge, invertebrates, and sediments appear to be a rich source for
secondary metabolites, possessing Antibiotic, antiviral, antifungal and antiyeast
activities. Besides, a few growth stimulant properties which may be useful in
studies on wound healing, carcinogenic properties, and in the study of cancers
are reported. Recent investigations on marine filamentous fungi looking for
biologically active secondary metabolites indicate the tremendous potential of
them as a source of new medicines. The present study reviews about some important
bioactive metabolites reported from marine fungal strains which are anti
bacterial, anti tumour and anti inflammatory in action. It highlights the
chemistry and biological activity of the major bioactive alkaloids, polyketides,
terpenoids, isoprenoid and non-isoprenoid compounds, quinones, isolated from
marine fungi.