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2017 ; 62
(1
): 62-66
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Major Depression Prevalence Increases with Latitude in Canada
#MMPMID27729573
Patten SB
; Williams JV
; Lavorato DH
; Wang JL
; Bulloch AG
Can J Psychiatry
2017[Jan]; 62
(1
): 62-66
PMID27729573
show ga
OBJECTIVE: To determine whether there is an association between latitude and
annual major depressive episode (MDE) prevalence in Canada. METHODS: Data from 2
national survey programs (the National Population Health Survey and the Canadian
Community Health Survey) were used, providing 10 data sets collected between 1996
and 2013, together including 922,260 respondents, of whom 495,739 were assessed
for MDE using 1 of 2 versions of the Composite International Diagnostic
Interview, a short-form version (8 studies), and a Canadian adaptation of the
World Mental Health version (2 studies). Approximate latitude was determined by
linkage to postal code data. Data were analyzed using logistic regression and
pooled across surveys using individual-level meta-analytic methods. RESULTS: In
models including latitude as a continuous variable, a statistically significant
association was observed, with prevalence increasing with increasing latitude.
This association persisted after adjustment for a set of known risk factors. The
latitude gradient was modest in magnitude, a 1% to 2% increase in the prevalence
odds of MDE per degree of latitude was observed. Due to sparse data, this
gradient cannot be confidently generalized beyond major population centres, which
tend to occur at less than 55° latitude in Canada. CONCLUSION: A latitude
gradient has not previously been reported. If replicated, the gradient may have
implications for the planning of services and generation of aetiological
hypotheses. However, this cross-sectional analysis cannot confirm aetiology and
could not evaluate the potential contributions of variables such as light
exposure, weather patterns, or social determinants.