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10.1073/pnas.1605941113

http://scihub22266oqcxt.onion/10.1073/pnas.1605941113
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suck abstract from ncbi


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pmid27601646
      Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (39 ): 10797-801
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  • Magnetite pollution nanoparticles in the human brain #MMPMID27601646
  • Maher BA ; Ahmed IA ; Karloukovski V ; MacLaren DA ; Foulds PG ; Allsop D ; Mann DM ; Torres-Jardón R ; Calderon-Garciduenas L
  • Proc Natl Acad Sci U S A 2016[Sep]; 113 (39 ): 10797-801 PMID27601646 show ga
  • Biologically formed nanoparticles of the strongly magnetic mineral, magnetite, were first detected in the human brain over 20 y ago [Kirschvink JL, Kobayashi-Kirschvink A, Woodford BJ (1992) Proc Natl Acad Sci USA 89(16):7683-7687]. Magnetite can have potentially large impacts on the brain due to its unique combination of redox activity, surface charge, and strongly magnetic behavior. We used magnetic analyses and electron microscopy to identify the abundant presence in the brain of magnetite nanoparticles that are consistent with high-temperature formation, suggesting, therefore, an external, not internal, source. Comprising a separate nanoparticle population from the euhedral particles ascribed to endogenous sources, these brain magnetites are often found with other transition metal nanoparticles, and they display rounded crystal morphologies and fused surface textures, reflecting crystallization upon cooling from an initially heated, iron-bearing source material. Such high-temperature magnetite nanospheres are ubiquitous and abundant in airborne particulate matter pollution. They arise as combustion-derived, iron-rich particles, often associated with other transition metal particles, which condense and/or oxidize upon airborne release. Those magnetite pollutant particles which are
  • |Air Pollution/*analysis [MESH]
  • |Brain/*metabolism/ultrastructure [MESH]
  • |Humans [MESH]
  • |Magnetite Nanoparticles/*chemistry/ultrastructure [MESH]
  • |Mexico [MESH]
  • |Particle Size [MESH]
  • |Spectrometry, X-Ray Emission [MESH]
  • |Spectroscopy, Electron Energy-Loss [MESH]


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