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2015 ; 42
(3
): 209-15
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Magnetic resonance imaging in pediatric pulmonary hypertension
#MMPMID26175631
Pektas A
; Olgunturk R
; Cevik A
; Terlemez S
; Kacar E
; Oner YA
Tex Heart Inst J
2015[Jun]; 42
(3
): 209-15
PMID26175631
show ga
The present study aims to determine the efficacy and reliability of
cardiovascular magnetic resonance imaging in establishing the diagnosis and
prognosis of pulmonary hypertension in children. This is a retrospective
comparison of 25 children with pulmonary hypertension and a control group
comprising 19 healthy children. The diagnosis of pulmonary hypertension was made
when the mean pulmonary artery pressure was ?25 mmHg by catheter angiography. The
children with pulmonary hypertension had significantly lower body mass indices
than did the healthy children (P=0.048). In addition, the children with pulmonary
hypertension had significantly larger main pulmonary artery diameters and
ascending aortic diameters (both P=0.001) but statistically similar ratios of
main pulmonary artery diameter-to-ascending aortic diameter. If the main
pulmonary artery diameter was ?25 mm, pediatric pulmonary hypertension was
diagnosed with 72% sensitivity and 84% specificity. In the event that the ratio
of main pulmonary artery diameter-to-ascending aorta diameter was ?1, pediatric
pulmonary hypertension was diagnosed with 60% sensitivity and 53% specificity.
When compared with children who had New York Heart Association functional class
II pulmonary hypertension, the children with functional class III pulmonary
hypertension had significantly larger main (P=0.046), right (P=0.036), and left
(P=0.003) pulmonary arteries. Cardiovascular magnetic resonance imaging is useful
in the diagnosis of children with pulmonary hypertension. Pediatric pulmonary
hypertension can be diagnosed with high sensitivity and specificity when the main
pulmonary artery diameter measures ?25 mm.