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2015 ; 2
(ä): e779
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Macrophage cell death upon intracellular bacterial infection
#MMPMID26690967
Lai XH
; Xu Y
; Chen XM
; Ren Y
Macrophage (Houst)
2015[Apr]; 2
(ä): e779
PMID26690967
show ga
Macrophage-pathogen interaction is a complex process and the outcome of this
tag-of-war for both sides is to live or die. Without attempting to be
comprehensive, this review will discuss the complexity and significance of the
interaction outcomes between macrophages and some facultative intracellular
bacterial pathogens as exemplified by Francisella, Salmonella, Shigella and
Yersinia. Upon bacterial infection, macrophages can die by a variety of ways,
such as apoptosis, autophagic cell death, necrosis, necroptosis, oncosis,
pyronecrosis, pyroptosis etc, which is the focus of this review.