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2015 ; 11
(9
): 1015-22
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MIND diet slows cognitive decline with aging
#MMPMID26086182
Morris MC
; Tangney CC
; Wang Y
; Sacks FM
; Barnes LL
; Bennett DA
; Aggarwal NT
Alzheimers Dement
2015[Sep]; 11
(9
): 1015-22
PMID26086182
show ga
INTRODUCTION: The Mediterranean and dash diets have been shown to slow cognitive
decline; however, neither diet is specific to the nutrition literature on
dementia prevention. METHODS: We devised the Mediterranean-Dietary Approach to
Systolic Hypertension (DASH) diet intervention for neurodegenerative delay (MIND)
diet score that specifically captures dietary components shown to be
neuroprotective and related it to change in cognition over an average 4.7 years
among 960 participants of the Memory and Aging Project. RESULTS: In adjusted
mixed models, the MIND score was positively associated with slower decline in
global cognitive score (? = 0.0092; P < .0001) and with each of five cognitive
domains. The difference in decline rates for being in the top tertile of MIND
diet scores versus the lowest was equivalent to being 7.5 years younger in age.
DISCUSSION: The study findings suggest that the MIND diet substantially slows
cognitive decline with age. Replication of these findings in a dietary
intervention trial would be required to verify its relevance to brain health.
|*Diet, Mediterranean
[MESH]
|Aged, 80 and over
[MESH]
|Aging/*psychology
[MESH]
|Chicago/epidemiology
[MESH]
|Cognition Disorders/*diet therapy/*epidemiology/prevention & control
[MESH]
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free
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