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10.4161/adip.32209 http://scihub22266oqcxt.onion/10.4161/adip.32209 C4496976!4496976 !26167404     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26167404 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26167404 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Adipocyte 2015 ; 4 (1 ): 60-4 Nephropedia Template TP {{tp|p=26167404 |t=2015. MAGP1, the extracellular matrix, and metabolism |pdf=|usr=}}{{26167404 }} gab.com Text MAGP1, the extracellular matrix, and metabolism JO: Adipocyte http://www.kidney.de/pget.php?&tw=1&pmid=26167404 #FOAvip Adipose tissue and the extracellular matrix were once considered passive players in regulating physiological processes. Now, both entities are acknowledged for their capacity to engage signal transduction pathways, and for their involvement in maintaining normal tissue homeostasis. We recently published a series of studies that identified a novel mechanism whereby an extracellular matrix molecule, MAGP1 (microfibril associated glycoprotein 1), can regulate energy metabolism in adipose tissue. MAGP1 is a component of extracellular microfibrils and plays a supportive role in maintaining thermoregulation by indirectly regulating expression of the thermogenic uncoupling proteins (UCPs). The focus of this commentary is to draw attention to the role of the extracellular matrix in regulating the bioavailability of signaling molecules, like transforming growth factor ? (TGF?), and exemplify that a better understanding of the extracellular matrix's biological properties could unveil a new source of therapeutic targets for metabolic diseases. Twit Text FOAVip MAGP1, the extracellular matrix, and metabolism ????Adipocyte http://www.kidney.de/pget.php?&tw=1&pmid=26167404 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26167404 #FOAvip English Wikipedia <ref>{{Cite pmid|26167404 }}</ref> MAGP1, the extracellular matrix, and metabolism #MMPMID26167404 Craft CS Adipocyte 2015[Jan]; 4 (1 ): 60-4 PMID26167404 show ga Adipose tissue and the extracellular matrix were once considered passive players in regulating physiological processes. Now, both entities are acknowledged for their capacity to engage signal transduction pathways, and for their involvement in maintaining normal tissue homeostasis. We recently published a series of studies that identified a novel mechanism whereby an extracellular matrix molecule, MAGP1 (microfibril associated glycoprotein 1), can regulate energy metabolism in adipose tissue. MAGP1 is a component of extracellular microfibrils and plays a supportive role in maintaining thermoregulation by indirectly regulating expression of the thermogenic uncoupling proteins (UCPs). The focus of this commentary is to draw attention to the role of the extracellular matrix in regulating the bioavailability of signaling molecules, like transforming growth factor ? (TGF?), and exemplify that a better understanding of the extracellular matrix's biological properties could unveil a new source of therapeutic targets for metabolic diseases. äMAGP1, the extracellular matrix, and metabolism (epmc).pdf DeepDyve Pubget Overpricing