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2020 ; 21
(2
): 69-75
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Liver transplantation in the era of COVID-19
#MMPMID32439237
El Kassas M
; Alboraie M
; Al Balakosy A
; Abdeen N
; Afify S
; Abdalgaber M
; Sherief AF
; Madkour A
; Abdellah Ahmed M
; Eltabbakh M
; Salaheldin M
; Wifi MN
Arab J Gastroenterol
2020[Jun]; 21
(2
): 69-75
PMID32439237
show ga
Liver transplantation is considered the ultimate solution for patients with
end-stage chronic liver disease or acute liver failure. Patients with liver
transplant need special care starting from preoperative preparation, surgical
intervention ending with postoperative care. Transplanted patients have to
receive immunosuppressive therapy to prevent rejection. Such a state of immune
suppression could predispose to different types of infections in liver transplant
recipients. Currently, the world is suffering a pandemic caused by a new strain
of the coronavirus family called COVID-19. Certain infection control precautions
are needed to protect immunocompromised and vulnerable patients, including liver
transplant candidates and recipients from acquiring COVID-19 infection.
Restricting non-transplant elective surgical procedures, managing transplant
patients in separate outpatient clinics, and in-patient wards can prevent
transmission of infection both to patients and healthcare workers. Telemedicine
can help in the triage of patients to screen for symptoms of COVID-19 before
their regular appointment. Management of immunosuppressive therapy and drug-drug
interactions in liver transplant recipients infected with COVID-19 should be
cautiously practiced to prevent rejection and effectively treat the underlying
infection. In this report, we are trying to summarize available evidence about
different aspects of the management of liver transplant candidates and recipients
in the era of COVID-19.
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