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10.1101/cshperspect.a016816

http://scihub22266oqcxt.onion/10.1101/cshperspect.a016816
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C3783046!3783046 !24086044
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suck abstract from ncbi


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pmid24086044
      Cold+Spring+Harb+Perspect+Biol 2013 ; 5 (10 ): a016816
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  • Lipid sorting and multivesicular endosome biogenesis #MMPMID24086044
  • Bissig C ; Gruenberg J
  • Cold Spring Harb Perspect Biol 2013[Oct]; 5 (10 ): a016816 PMID24086044 show ga
  • Intracellular organelles, including endosomes, show differences not only in protein but also in lipid composition. It is becoming clear from the work of many laboratories that the mechanisms necessary to achieve such lipid segregation can operate at very different levels, including the membrane biophysical properties, the interactions with other lipids and proteins, and the turnover rates or distribution of metabolic enzymes. In turn, lipids can directly influence the organelle membrane properties by changing biophysical parameters and by recruiting partner effector proteins involved in protein sorting and membrane dynamics. In this review, we will discuss how lipids are sorted in endosomal membranes and how they impact on endosome functions.
  • |*Lipid Metabolism [MESH]
  • |Biological Transport [MESH]
  • |Cholesterol/metabolism [MESH]
  • |Endosomes/*metabolism [MESH]
  • |Intracellular Membranes/chemistry/metabolism [MESH]
  • |Membrane Lipids [MESH]
  • |Models, Biological [MESH]
  • |Phosphatidylinositols/biosynthesis/metabolism [MESH]


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