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10.1038/nn.4220 http://scihub22266oqcxt.onion/10.1038/nn.4220 C4927193!4927193 !26814589     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26814589 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Neurosci 2016 ; 19 (2 ): 198-205 Nephropedia Template TP {{tp|p=26814589 |t=2016. Lateral hypothalamic circuits for feeding and reward |pdf=|usr=}}{{26814589 }} gab.com Text Lateral hypothalamic circuits for feeding and reward JO: Nat Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=26814589 #FOAvip In experiments conducted over 60 years ago, the lateral hypothalamic area (LHA) was identified as a critical neuroanatomical substrate for motivated behavior. Electrical stimulation of the LHA induces voracious feeding even in well-fed animals. In the absence of food, animals will work tirelessly, often lever-pressing thousands of times per hour, for electrical stimulation at the same site that provokes feeding, drinking and other species-typical motivated behaviors. Here we review the classic findings from electrical stimulation studies and integrate them with more recent work that has used contemporary circuit-based approaches to study the LHA. We identify specific anatomically and molecularly defined LHA elements that integrate diverse information arising from cortical, extended amygdala and basal forebrain networks to ultimately generate a highly specified and invigorated behavioral state conveyed via LHA projections to downstream reward and feeding-specific circuits. Twit Text FOAVip Lateral hypothalamic circuits for feeding and reward ????Nat Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=26814589 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26814589 #FOAvip English Wikipedia <ref>{{Cite pmid|26814589 }}</ref> Lateral hypothalamic circuits for feeding and reward #MMPMID26814589 Stuber GD ; Wise RA Nat Neurosci 2016[Feb]; 19 (2 ): 198-205 PMID26814589 show ga In experiments conducted over 60 years ago, the lateral hypothalamic area (LHA) was identified as a critical neuroanatomical substrate for motivated behavior. Electrical stimulation of the LHA induces voracious feeding even in well-fed animals. In the absence of food, animals will work tirelessly, often lever-pressing thousands of times per hour, for electrical stimulation at the same site that provokes feeding, drinking and other species-typical motivated behaviors. Here we review the classic findings from electrical stimulation studies and integrate them with more recent work that has used contemporary circuit-based approaches to study the LHA. We identify specific anatomically and molecularly defined LHA elements that integrate diverse information arising from cortical, extended amygdala and basal forebrain networks to ultimately generate a highly specified and invigorated behavioral state conveyed via LHA projections to downstream reward and feeding-specific circuits. |*Reward [MESH] |Animals [MESH] |Electric Stimulation [MESH] |Feeding Behavior/*physiology [MESH] |Humans [MESH] |Hypothalamic Area, Lateral/*physiology [MESH] |Motivation [MESH]Lateral hypothalamic circuits for feeding and reward (epmc).pdf DeepDyve Pubget Overpricing