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2015 ; 22
(6
): 1115-9
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KnowEnG: a knowledge engine for genomics
#MMPMID26205246
Sinha S
; Song J
; Weinshilboum R
; Jongeneel V
; Han J
J Am Med Inform Assoc
2015[Nov]; 22
(6
): 1115-9
PMID26205246
show ga
We describe here the vision, motivations, and research plans of the National
Institutes of Health Center for Excellence in Big Data Computing at the
University of Illinois, Urbana-Champaign. The Center is organized around the
construction of "Knowledge Engine for Genomics" (KnowEnG), an E-science framework
for genomics where biomedical scientists will have access to powerful methods of
data mining, network mining, and machine learning to extract knowledge out of
genomics data. The scientist will come to KnowEnG with their own data sets in the
form of spreadsheets and ask KnowEnG to analyze those data sets in the light of a
massive knowledge base of community data sets called the "Knowledge Network" that
will be at the heart of the system. The Center is undertaking discovery projects
aimed at testing the utility of KnowEnG for transforming big data to knowledge.
These projects span a broad range of biological enquiry, from pharmacogenomics
(in collaboration with Mayo Clinic) to transcriptomics of human behavior.
free
free
free
